By Chien-Min Wang, Chun-Chen Hsu, Pangfeng Liu, Hsi-Min Chen, Jan-Jan Wu (auth.), Yeh-Ching Chung, José E. Moreira (eds.)
This e-book constitutes the refereed complaints of the 1st foreign convention on Grid and Pervasive Computing, GPC 2006, held in Taichung, Taiwan, in might 2006.
The sixty four revised complete papers have been conscientiously reviewed and chosen from 267 submissions. The papers are geared up in topical sections on grid scheduling, peer-to-peer computing, Web/grid companies, excessive functionality computing, advert hoc networks, instant sensor networks, grid functions, information grid, pervasive functions, semantic net, semantic grid, grid load balancing, instant advert hoc/sensor networks, and cellular computing.
Read Online or Download Advances in Grid and Pervasive Computing: First International Conference, GPC 2006, Taichung, Taiwan, May 3-5, 2006. Proceedings PDF
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Additional resources for Advances in Grid and Pervasive Computing: First International Conference, GPC 2006, Taichung, Taiwan, May 3-5, 2006. Proceedings
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13 (1999) 3191–3197 6. : Expression proﬁling reveals oﬀ-target gene regulation by RNAi. Nature Biotechnology 21 (2003) 635–637 7. : Small RNAs with imperfect match to endogenous mRNA repress translation. J. Bio. Chemistry 278(45) (2003) 44312–44319 8. : A computational study of oﬀ-target eﬀects of RNA interference. Nucleic Acids Research 33 (2005) 1834–1847 9. : Basic local alignment search tool. J. Mol. Biol. 215 (1990) 403–410 10.
Programs were written in C++ using p–threads. Fig. 2 displays SS3’s speedups using input-partition, indicating that more than 8 fold speedups were achieved. However, the speedups were less than linear and even decreased with more processors in some cases. This decrease of speedup is attributed to the drawbacks of the computer architecture. Since our BSTs were shared by all processors, bus contention and deep cache hierarchy deteriorate performance greatly with the increase of processors. The ﬁgures also show that more speedups were achieved for longer mismatches.
RNAi has been regarded as a highly eﬀective means of gene repression[2, 5]. However, its eﬀectiveness can be compromised by nonspeciﬁc, or oﬀ-target knockdown, which is the unintentional silencing of a gene other than the target. In this paper, we develop eﬃcient algorithms searching whole transcriptomes to detect targets of siRNA and dsRNA for target validation. Although RNAi is predominantly considered highly speciﬁc , signiﬁcant nonspeciﬁc gene knockdowns have been reported [6, 7, 8]. Experiments in human cells found silencing of nontarget genes containing only 11 nt identity to the siRNA .
Advances in Grid and Pervasive Computing: First International Conference, GPC 2006, Taichung, Taiwan, May 3-5, 2006. Proceedings by Chien-Min Wang, Chun-Chen Hsu, Pangfeng Liu, Hsi-Min Chen, Jan-Jan Wu (auth.), Yeh-Ching Chung, José E. Moreira (eds.)